CRCHUM

Laboratoire de biorhéologie et d'ultrasonographie médicale

The Laboratory of Biorheology and Medical Ultrasonics (LBMU) pursues researches in medical imaging and blood rheology. Our research programs intend to improve the diagnostic and follow-up of hyper-erythrocyte aggregation, a pathological state promoting the hyper-viscosity of blood and thrombotic side effects, arterial atherosclerosis, vascular aneurysms, deep vein thrombosis, breast tumors, liver steatosis and tendon pathologies with new imaging methods. The LBMU is also developing new methods to characterize the biomechanical properties of the vascular wall with ultrasound elastography. These research projects are realized in collaboration with clinical scientists, radiologists and cardiologists, fundamental scientists specialized in cardiovascular pathologies, biomedical engineers, and medical physicists. The LBMU is a Laboratory located in the research center of the University of Montreal Hospital. It is part of the Imaging and Bioengineering research axis of the University of Montreal Hospital Research Center. The LBMU is directed by Dr Guy Cloutier, who is also Professor and Director of research in the Department of Radiology, Radio-oncology and Nuclear Medicine of theUniversity of Montréal, and member of the Institut de génie biomédical (IGB) of the University of Montréal.

News

  • Pr François Yu joint LBUM's team

    Dr Yu is an assistant professor at the Department of Radiology, Radio-oncology and Nuclear Medicine at the Université de Montréal and Independent Researcher at the Centre de recherche du centre hospitalier de l’Université de Montréal since 08/2017. Dr Yu received his B.S. degree in electrical engineering in 2001 from the École Polytechnique de Montréal, Canada, and his Ph.D. degree in Biomedical Engineering in 2010 from the Université de Montréal. He has a strong background in high frequency ultrasound imaging of diseases associated with blood rheological disorders, including diabetes, atherosclerotic plaque characterization, and deep vein thrombosis. He pursued his postodoctoral training at the Center for Ultrasound Molecular Imaging and Therapeutics at the University of Pittsburgh where developed an expertise in the use of MB (US contrast agent) for diagnostic and therapeutic application in cardiology and oncology.

    Specifically, Dr Yu’s research interests focus on developing spatially targeted therapeutic strategies using MBs externally triggered by therapeutic US and monitored using US imaging forming a versatile theranostic platform. In particular, he is interested in elucidating the signaling pathways and harnessing the physiological response following ultrasound stimulated microbubble oscillations to create clinically translatable theranostic targeted therapies. In his laboratory, there are opportunities to work at many levels of research and technological development, including US pulsing and image processing, microbubble synthesis, in vitro validation, in vivo rodent animal models, human bio-samples, cell culture and molecular biology techniques. This multidisciplinary environment contributes to shape a unique perspective on opportunities and challenges for novel theranostic developments.

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  • Pictures gallery of the LBUM